Archive for February, 2010

Health Tip: Signs That You Have Cataracts

Thursday, February 25th, 2010

Cataracts are an eye condition characterized by a cloudiness of the eye’s lens. They usually develop slowly as a person gets older.

The U.S. National Library of Medicine offers this list of cataract symptoms:
Vision that appears foggy or cloudy; as if there’s a film over the eye.
Inability to see colors as vividly as before.
Seeing double.
Problems seeing well at night.
Seeing an aura or halo surrounding lights.
Increased sensitivity to glaring lights.
Difficulty in differentiating shapes or similar colors.

Poor nutrition stunts growth of 200 million children: U.N.

Wednesday, February 17th, 2010

Nearly 200 million children in developing countries suffer from stunted growth and health problems due to poor nutrition in their early years, the U.N. children’s foundation UNICEF said on Wednesday.

However, the percentage of children with retarded growth in Asia fell to 30 percent last year from 44 percent in 1990, and in Africa to 34 percent from 38 percent over the same period, UNICEF said in a report.

Despite a decline in the rate of the problem, 195 million children in developing countries under 5 years old have stunted growth due to poor nutrition during the critical period between their conception and second birthdays, UNICEF said.

Undernourished children often have poor physical health and slower mental development. When the problem is widespread, as in India and Afghanistan, it undermines those countries’ ability to improve their economies and eradicate poverty.

“Undernutrition steals a child’s strength and makes illnesses that the body might otherwise fight off far more dangerous,” UNICEF Executive Director Ann Veneman said in a statement.

“More than one third of children who die from pneumonia, diarrhea and other illnesses could have survived had they not been undernourished,” she said.

More than 90 percent of the developing world’s children facing stunted growth live in Africa and Asia, the report said. A third of them — roughly 60.8 million — are in India.

UNICEF said that countries with the highest prevalence of stunted growth among children under the age of five include Afghanistan (59 percent), Yemen (58 percent), Guatemala and East Timor (both 54 percent), Democratic Republic of the Congo (46 percent) and North Korea (45 percent).

India, the world’s second most-populous country, continues to have a high rate of children under 5 years old suffering from retarded growth, though it fell from around 52 percent in 1992-1993 to 43 percent in 2005-2006, UNICEF said.

Veneman told reporters on a conference call that roughly 8.8 million children are dying every year from largely preventable causes and poor nutrition is a contributing factor in more than a third of those deaths.

She added that the issue of access to proper nutrition for impoverished children and pregnant and breastfeeding mothers was related to the larger issue of poor food security in a world where some 1 billion people are hungry or malnourished.

The 1,000 days from conception until a child’s second birthday are the most important for growth and development, the report said. Insufficient nutrition during this period can permanently harm the body’s ability to ward off and overcome diseases and damage a child’s social and mental development.

Stunted growth, UNICEF said, can rarely be corrected. However, Veneman said it can be prevented and programs to improve access to iodized salt and vitamin A supplements in Africa and Asia have improved the situation in some countries — and led to a reduction in infant and child mortality.

Sharing Prescriptions Can Bring Harm, Not Healing

Wednesday, February 10th, 2010

Sharing prescription medication with a family member or friend who needs care may seem like the right thing to do, even an act of kindness. But new research highlights the potential hazards of passing these medicines around.

Of people who borrowed a medicine prescribed for someone else, 25.1 percent experienced some sort of side effect, researchers reported Wednesday at the American Public Health Association annual meeting in Philadelphia.

While 77.3 percent of prescription borrowers said they had bummed medicine rather than see a health-care provider, for many it merely delayed the inevitable. That’s because one in three ended up seeking medical care, anyway.

A lot of people have focused on “recreational medication sharing,” or abuse of prescription drugs “for a buzz,” explained lead investigator Richard C. Goldsworthy, director of research and development at The Academic Edge, a Bloomington, Ind.-based developer of educational media.

“What people haven’t looked at is what we started to call ‘altruistic medication sharing,’” he said. “It’s ‘You’re not feeling so well,’ and a friend happens to have some extra medicine of a certain kind that treats symptoms similar to what you’re having, and they let you borrow it.”

In an earlier study, Goldsworthy and colleagues reported that 20 percent of U.S. teens say they swap prescription drugs such as antibiotics and allergy medicines with friends. The new study corroborates the frequency of drug-sharing in America, with one in five admitting to borrowing drugs.

Many people just think it’s “no big deal,” he explained.

Yet depending on the drug, the dosage and other factors, it can be a very big deal, one expert cautioned.

“There’s always been an issue, especially with medications such as pain medications,” said Allen J. Vaida, executive vice president at the Institute for Safe Medication Practices (ISMP), in Horsham, Pa.

Painkillers come in different dosages and some combine, say, an opioid with acetaminophen (the active ingredient in Tylenol), he said. If the borrower is already taking an over-the-counter pain reliever, such as Tylenol, he or she could be doubling the dose of acetaminophen, Vaida said.

In one tragic case, a 6-year-old with neck pain was found unconscious in bed the day after her foster mother placed a leftover fentanyl patch on the girl’s neck, ISMP reported. The child died before reaching the emergency room.

But pain medications are not the sole cause of unintentional consequences. Sharing eye-drops can result in the spread of infection, Vaida noted. Doling out leftover antibiotics can result in unnecessary treatment or treatment with the wrong antibiotic, he said. And taking someone else’s anti-anxiety medicine without the proper warnings can cause unanticipated dizziness or sleepiness behind the wheel of a car.

A week ago, the U.S. Food and Drug Administration (FDA) launched a new campaign aimed at reducing “preventable harm” from medication use. Taking medication meant for other people is among the potential dangers it highlighted.

“Too many people suffer unnecessary injuries from avoidable medication misuse, errors, and other problems,” FDA Commissioner Dr. Margaret A. Hamburg said in a statement. FDA is launching the Safe Use Initiative to develop targeted solutions for reducing these injuries.

To find out whether drug sharing is putting people in harm’s way, Goldsworthy had trained field agents conduct one-on-one interviews of almost 2,800 people in 11 different markets.

Of those who admitted to borrowing prescription medicines, many never got written (54.6 percent) or verbal (38.2 percent) warnings or instructions from the person loaning the medicine.

Among people who delayed seeking care, half of them never told their health-care provider that they had taken a borrowed medication.

“On the side effects, we don’t actually know the severity. It’s actually a limitation of the study,” Goldsworthy said. “And we also don’t know, in the analysis we’ve done so far, how many of those are actually people who sought a side effect.”

Still, the prevalence of side effects suggests that the risk for harm is a real possibility.

Avoiding unintended health consequences begins with education, Vaida said. Physicians, pharmacists and nurses need to tell patients not to share their medicines with family or friends, he explained.

People should also get in the habit of cleaning out their medicine cabinets and turning over leftover and unused drugs to community “take-back” programs, he added.

“That’s probably something that should be done all the time in every community,” Vaida said.

Early Use of NSAIDs Might Prevent Alzheimer’s

Wednesday, February 3rd, 2010

Taking nonsteroidal anti-inflammatory drugs (NSAIDs) from a young age might prevent early signs of Alzheimer’s disease, according to the results of a new study in mice.

Recent research suggests that the appearance of neuronal cell cycle events (CCEs) occurs early in the development of Alzheimer’s. In the new study, U.S. researchers looking for triggers of neuronal CCEs found evidence that suggests that neuroinflammation plays a role in the development of Alzheimer’s in mice.

Administration of the inflammatory molecule LPS triggered the early appearance of neuronal CCEs, the researchers found, and treatment with the NSAIDs ibuprofen or naproxen blocked the development of CCEs.

In older mice, treatment with NSAIDs prevented new neuronal CCEs but did not affect existing CCEs, the study authors noted.

The study, published online Nov. 9 in the Journal of Clinical Investigation, offers a potential explanation for findings in humans that long-term NSAID use protects against Alzheimer’s but does not benefit people who already have mild to moderate Alzheimer’s disease.